Table 2.
Characteristics and percent change at 30-month follow-up stratified by omega-3 fatty acid index group
| Low Omega-3 Fatty Acid Index (n = 15) 2.4% [2.3, 2.7] |
High Omega-3 Fatty Acid Index (n = 16) 8.4% [8.1, 9.6] |
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|---|---|---|---|---|---|
| 30-Month Absolute Value (IQR or SD) | Median % Change [IQR] at 30 months compared to Baseline | 30-Month Absolute Value (IQR or SD) | Median % Change [IQR] at 30 months compared to Baseline | Between group P value † | |
| BMI, kg/m2 | 31.2 (2.6) | 2.7 [−1.2, 5.4] | 31.0 (3.6) | −3.26 [−4.4, 4.0] | 0.097 |
| Blood Pressure, mm Hg, mean (SD) | |||||
| Systolic BP | 121.1 (14.2) | −5.8 [−11.9, 6.9] | 116.3 (10.1) | 3.3 [−7.1, 9.4] | 0.26 |
| Diastolic BP | 74.6 (7.7) | −3.5 [−10.6, 17.8] | 71.0 (8.7) | 0.0 [−4.5, 3.6] | 0.88 |
| Biochemical Profile, mean (SD) except hs-CRP which is median [interquartile range] | |||||
| Glucose, mmol/L mg/dL | 5.82 (1.98) | 1.0 [−4.3, 7.1] | 4.90 (0.49) | −1.58 [−4.1, 4.1] | 0.24 |
| 104.8 (35.7) | 88.3 (8.9) | ||||
| hs-CRP, nmol/L mg/L | 18.1 [6.7, 36.2] | 26.5 [−57.3, 56.5] | 8.6 [1.9, 30.5] | −48.39 [−66.0, −4.6] | 0.14 |
| 1.9 [0.7, 3.8] | 0.9 [0.2, 3.2] | ||||
| Lipid profile, mean (SD) except triglyceride which is median [interquartile range] | |||||
| Total cholesterol, mmol/L mg/dL | 4.13 (0.93) | 0.0 [−10.2, 18.4] | 4.21 (1.27) | −10.6 [−15.0, 6.1] | 0.28 |
| 159.3 (35.9) | 162.7 (49.2) | ||||
| Triglyceride, mmol/L mg/dL | 1.48 [1.10,2.59] | 14.9 [−14.4, 25.1] | 0.95 [0.76,1.47] | −18.3 [−31.0, −7.8] | 0.025 |
| 131.0 [97.0, 229.0] | 84.5 [67.5, 130.0] | ||||
| HDL-C, mmol/L mg/dL | 1.10 (0.26) | −5.3 [−10.6, 4.4] | 1.30 (0.27) | −5.7 [−17.2, 4.5] | 0.92 |
| 42.4 (9.9) | 50.3 (10.6) | ||||
| LDL-C, mmol/L mg/dL | 2.19 (0.90) | 16.3 [−18.0, 32.2] | 2.32 (1.01) | −8.8 [−23.0, 12.2] | 0.50 |
| 84.6 (34.7) | 89.4 (39.1) | ||||
| Complete blood count, mean (SD) | |||||
| WBC, 109 cells/L | 6.8 (2.7) | −6.9 [−21.4, 4.8] | 6.5 (1.7) | −0.62 [−6.0, 7.1] | 0.20 |
| Monocytes, cells/μL | 527.5 (154.3) | −6.29 [−24.3, 19.0] | 477.8 (157.2) | −0.8 [−10.4, 17.4] | 0.44 |
| Neutrophils, cells/μL | 4841.5 (2633.7) | −4.71 [−24.7, 8.3] | 3837.8 (1481.5) | −5.6 [−20.7, 7.6] | 0.70 |
| Lymphocytes, cells/μL | 1252.9 (655.0) | −18.33 [−32.4, −8.2] | 1954.9 (722.7) | 6.3 [−16.4, 29.4] | 0.008 |
†
P Value comparing % change between groups (low omega-3 fatty acid index compared to high omega-3 fatty acid index) at 30-month follow-up with Mann-Whitney U test.
BMI, body mass index; BP, blood pressure; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high-sensitivity C-reactive protein; LDL-C, low-density lipoprotein cholesterol; WBC, white blood cell count.