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. 2021 Mar 24;13(7):1497. doi: 10.3390/cancers13071497

Figure 1.

Figure 1

CONSORT diagram showing which QUASAR 2 samples were available for genotyping the variants meeting inclusion criteria 1 and 2. 22 Variants considered for inclusion in the panel are displayed. Those in bold have high quality evidence of a genotype to DPD phenotype in the CPIC 2018 guidelines. Variants that are underlined are the extra DPYD deficiency alleles under consideration based on criteria 2. The remainder are common variants fitting inclusion criteria 1. Those for which at least one variant allele was detected in QUASAR2 are marked with a *.