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. 2021 Mar 30;13(7):1592. doi: 10.3390/cancers13071592

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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(A–D): Sankey diagrams showing the PAM50 breast cancer intrinsic subtype shifts of matched samples between (A) the primary tumor (PT) and lymph node metastasis (LNM) (n = 59); (B) the PT and distant metastasis (DM) (n = 61); (C) LNM and DM (n = 38); and (D) the PT, LNM, and DM (n = 33). Abbreviations: HER2-E: human epidermal growth factor receptor 2-enriched; Lum A/B: luminal A/B.

(A–D): Sankey diagrams showing the PAM50 breast cancer intrinsic subtype shifts of matched samples between (A) the primary tumor (PT) and lymph node metastasis (LNM) (n = 59); (B) the PT and distant metastasis (DM) (n = 61); (C) LNM and DM (n = 38); and (D) the PT, LNM, and DM (n = 33). Abbreviations: HER2-E: human epidermal growth factor receptor 2-enriched; Lum A/B: luminal A/B.