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. 2021 Mar 26;22(7):3419. doi: 10.3390/ijms22073419

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Electroretinography (ERG) and optical coherence tomography (OCT) measurements. (A) mfPERG stimulus with 36 checkerboard elements, where each element (dotted red) reverses the pattern between 1 and 0 states. The stimulus (xx° diameter) spanned 4 eccentricity ranges outlined by green line. (B) Macular vertical scan with segmentation line, (C) Early Treatment for Diabetic Retinopathy Study’s (ETDRS) circle, i.e., 1 mm (foveal), 3 mm (parafoveal), and 6 mm (perifoveal) circles, analysis of the ganglion cell layer (GCL), and (D) peripapillary area scan with different sector thickness. ILM = internal limiting membrane; RNFL = retinal nerve fiber layer thickness; GCL = ganglion cell layer; IPL = inner plexiform layer; INL = inner nuclear layer; OPL = outer plexiform layer; ELM = external limiting membrane; PR1 = photoreceptor inner segments; PR2 = photoreceptors outer segments; RPE = retinal pigment epithelium; BM = Bruch’s membrane. Peripapillary retinal nerve fiber layer thickness: G = global average thickness; T = temporal; PMB = papillomacular bundle; N/T: nasal/temporal ratio; S: superior; I: Inferior.