Table 1.
Demographic and clinical characteristics of the participants.
| Control (N = 14) | NON (N = 12) | HON (N = 11) | p-Value | |
|---|---|---|---|---|
| Age (y) | 41.0 [12.6] (20–60) |
42.0 [10.9] (27–61) |
39.0 [9.8] (25–52) |
0.803 |
| Female N (%) | 7 [50] | 8 [66.7] | 8 [72.7] | 0.384 |
| Disease duration (y) | - | 6.4 [4.6] (1–13) |
10.3 [8.0] (1–26) |
0.179 |
| BCVA (logMAR) | −0.02 (−0.1–0.00) | −0.02 (−0.1–0.1) | 0.00 (−0.1–0.1) | 0.54 |
| Median EDSS | - | 2.0 (1–7) | 1.5 (0–4.5) | 0.332 |
Unless otherwise reported mean [standard deviation] (range) is given; BCVA = best corrected visual acuity (logMAR = logarithm of minimum angle of resolution). EDSS = expanded disability status scale, HON = multiple sclerosis with a history of optic neuritis, N = number of subjects, NON = multiple sclerosis without a history of optic neuritis. Y = years. Disease duration was defined as timespan between symptom onset and visual measurements. Groups were compared with respect to categorical (using a c2-test) and continuous variables (using analysis of variance (ANOVA) or Kruskal–Wallis test and a t-test or Mann–Whitney U test).