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. 2021 Apr 2;22(7):3712. doi: 10.3390/ijms22073712

Figure 3.

Figure 3

Paw withdrawal responses (PWRs) to mechanical stimulation remained unaffected by intrathecal administration of TRPV1 endogenous agonist OLDA. Administration of OLDA (0.42 µg, n = 4) did not change the PWRs evoked by von Frey filaments with bending forces of small intensities ranging from 10 mN to 59 mN (A), and stronger intensities ranging from 80 mN to 370 mN (B) when compared to vehicle treatment (n = 6). Data represent the mean ± S.E.M. of 4 and 6 independent experiments. The time of the i.t. administration is marked by arrows.