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. 2021 Apr 2;13(7):1692. doi: 10.3390/cancers13071692

Table 3.

Nucleotide divergence and polymorphism in the non-repeat 2562 bp sequence regions.

Country n No. of Polynmorphic Sites No. of Substitutions Nucleotide Diversity Codon-Based Evolutionary Divergence
Synonymous Non-Synonymous π ± SD dS ± SE dN ± SE p Value
Malawi and Mozambique 115 29 12 17 0.00029 ± 0.00004 0.00050 ± 0.00012 0.00024 ± 0.00008 dS > dN: 0.0595
eBL case 63 17 8 9 0.00028 ± 0.00005 0.00055 ± 0.00017 0.00021 ± 0.00009 dS > dN: 0.0450
Control 52 16 6 10 0.00031 ± 0.00006 0.00044 ± 0.00017 0.00027 ± 0.00011 dS > dN: 0.1943
Tanzania 55 11 1 10 0.00021 ± 0.00007 0.00007 ± 0.00007 0.00025 ± 0.00008 dN > dS: 0.0549
Ghana 33 10 1 10 0.00032 ± 0.00011 0.00000 ± 0.00000 0.00040 ± 0.00015 dN > dS: 0.0034

π: nucleotide diversity, SD: standard deviation, dS: the numbers of synonymous substitutions per synonymous site, SE: standard error, dN: nonsynonymous substitutions per nonsynonymous site, eBL: endemic Burkitt Lymphoma.