Table 3.
Nucleotide divergence and polymorphism in the non-repeat 2562 bp sequence regions.
Country | n | No. of Polynmorphic Sites | No. of Substitutions | Nucleotide Diversity | Codon-Based Evolutionary Divergence | |||
---|---|---|---|---|---|---|---|---|
Synonymous | Non-Synonymous | π ± SD | dS ± SE | dN ± SE | p Value | |||
Malawi and Mozambique | 115 | 29 | 12 | 17 | 0.00029 ± 0.00004 | 0.00050 ± 0.00012 | 0.00024 ± 0.00008 | dS > dN: 0.0595 |
eBL case | 63 | 17 | 8 | 9 | 0.00028 ± 0.00005 | 0.00055 ± 0.00017 | 0.00021 ± 0.00009 | dS > dN: 0.0450 |
Control | 52 | 16 | 6 | 10 | 0.00031 ± 0.00006 | 0.00044 ± 0.00017 | 0.00027 ± 0.00011 | dS > dN: 0.1943 |
Tanzania | 55 | 11 | 1 | 10 | 0.00021 ± 0.00007 | 0.00007 ± 0.00007 | 0.00025 ± 0.00008 | dN > dS: 0.0549 |
Ghana | 33 | 10 | 1 | 10 | 0.00032 ± 0.00011 | 0.00000 ± 0.00000 | 0.00040 ± 0.00015 | dN > dS: 0.0034 |
π: nucleotide diversity, SD: standard deviation, dS: the numbers of synonymous substitutions per synonymous site, SE: standard error, dN: nonsynonymous substitutions per nonsynonymous site, eBL: endemic Burkitt Lymphoma.