Table 5.
Genetic differentiation (Fst) of the P. falciparum sera5.
| P. falciparum sera5Region/Country | Subject Type | Malawi and Mozambique | Tanzania | Ghana | ||
|---|---|---|---|---|---|---|
| All | eBL Case | Control | All | All | ||
| (A) Octamer repeat region | ||||||
| Malawi and Mozambique | Combined | - | 0.9910 | 0.9910 | 0.0721 | 0.0360 |
| eBL case | −0.0094 | - | 0.4595 | 0.1171 | 0.0090 | |
| Control | −0.0097 | −0.0030 | - | 0.0811 | 0.0270 | |
| Tanzania | All subjects | 0.0113 | 0.0085 | 0.0130 | - | 0.0811 |
| Ghana | All subjects | 0.0291 | 0.0271 | 0.0286 | 0.0104 | - |
| (B) Serine repeat region | ||||||
| Malawi and Mozambique | Combined | - | 0.9910 | 0.9910 | 0.0811 | 0.0000 |
| eBL case | −0.0093 | - | 0.6216 | 0.0541 | 0.0000 | |
| Control | −0.0096 | −0.0027 | - | 0.3604 | 0.0451 | |
| Tanzania | All subjects | 0.0069 | 0.0100 | 0.0013 | - | 0.2072 |
| Ghana | All subjects | 0.0202 | 0.0204 | 0.0181 | 0.0039 | - |
| (C) Non-repeat 2562 bp sequence | ||||||
| Malawi and Mozambique | Combined | - | 0.9910 | 0.9910 | 0.2973 | 0.5676 |
| eBL case | −0.0099 | - | 0.9279 | 0.4234 | 0.5946 | |
| Control | −0.0105 | −0.0056 | - | 0.2342 | 0.8018 | |
| Tanzania | All subjects | 0.0011 | −0.0002 | 0.0023 | - | 0.5586 |
| Ghana | All subjects | −0.0033 | −0.0037 | −0.0067 | −0.0044 | - |
Fst values are shown in the bottom left and p-values are shown in the upper right. p < 0.05 are shown in bold. eBL: endemic Burkitt Lymphoma.