Table 4.
Review of the literature. Studies reporting margins based on UICC classification.
| Study | Margins | Sample Size | Histotypes | Tumor Grade | Median Follow Up (Months) | LR Rate | Margin Indipendent Prognostic Factor for LR? | Other Prognostic Factors for LR? | Homogeneous Cohort |
|---|---|---|---|---|---|---|---|---|---|
| Gundle et al. [29] | R0% R1 R2 |
2217 | All Histotypes | All grades | 65 | 6.0% 10.0% 38.0% |
yes | Grade 3 Depth RT |
no |
| Kainhofer et al. [31] | R0% R1 |
265 | All histotypes | All grades | - | 12.0% 57.9% |
yes | Adjuvant ChT Tumor Depth |
no |
| Fuiiwara et al. [48] | R0% R1 R2 |
109 | All Histotypes | Grade 1 | 67 | 7.0% 14.0% 54.0% |
yes | Tumor Depth | no |
LR: local recurrence; RT: radiotherapy; ChT: chemotherapy.