Table 3.

Meta-analysis regarding the relationship between NAFLD and periodontal disease.

Ref. No.	Study	The Number of Primary Studies	Study Designs of Primary Studies	Statistical Analysis	Results
[50]	Chen et al. 2020 n = 118,408	12	Cross-sectional (4), case-control (1), cohort (7)	Generalized least-squares regressions	An association between periodontitis and NAFLD (OR = 1.19, 95% CI =1.06–1.33), and an association periodontitis and cirrhosis (OR = 2.28, 95% CI = 1.50–3.48) was reported.
[51]	Wijarnpreecha et al. 2020 n = 27,703	5	Cross-sectional (4), cohort (1)	PRISMA, The random-effect model	NAFLD was associated with periodontitis (OR = 1.48, 95% CI = 1.13–1.89), however, significant correlation was lost after the adjusted results of the primary studies were applied.

NAFLD: nonalcoholic fatty liver disease, PRISMA: Preferred Reporting Items for Systematic Reviews and Meta-analysis.