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. 2021 Apr 2;26(7):2048. doi: 10.3390/molecules26072048

Table 8.

Detailed analysis of compound 6 against docking in S. aureus tyrosyl-tRNA synthetase (PDB ID: 1jij) as a potential antibacterial target.

Type of Bond Distance (Å) Interacting Amino Acid of Target
Hydrogen Bond 3.02926 A:TYR170:OH
Hydrogen Bond 2.11983 A:THR75:OG1
Hydrogen Bond 2.07234 A:ASP80:OD2
Hydrogen Bond 2.66497 A:GLN196:OE1
Hydrogen Bond 3.53206 A:HIS50:CD2
Hydrogen Bond 2.08403 A:GLN196:OE1
Hydrophobic 4.41402 A:ALA39
Hydrophobic 5.21473 A:CYS37
Hydrophobic 4.58554 A:PRO53
Hydrophobic 4.46255 A:TYR36
Hydrophobic 4.44049 A:HIS50
Hydrophobic 4.45421 A:PHE54
Hydrophobic 5.31681 A:LEU70
Hydrophobic 4.82878 A:ALA39