Table 11.
Cytotoxicity and biodegradability studies, as reported by Erfurt et al. [72].
| IL | EC50 (μmol/L) 1 | EC50 (mg/L) 1 | Biodegradability 2 |
|---|---|---|---|
| 106a | >584 | >202 | 74–83% 3 |
| 108c | 85.1 (66.1–97.7) 4 | 42.6 (33.1–48.9) 4 | 57% 5 |
| 108d | 9.5 (8.9–10.2) 4 | 5.3 (5.0–5.7) 4 | 50–60% 6 |
| 108e | 13.5 (12.3–14.5) 4 | 10.2 (9.3–10.9) 4 | Not tested 7 |
| Carbendazim 8 | 8.1 (7.4–8.7) 4 | 1.6 (1.4–1.7) 4 | --- |
1 Evaluated on rat leukemia cell line IPC-81 using a WST-1 assay; 2 Two independent biodegradation tests were performed using the ready biodegradability test procedure according to the OECD 301F guideline; 3 Readily biodegradable; 4 Confidence interval; 5 Low persistence potential; 6 Longer lag phase (10 days), after which biodegradation started and continued until test termination without reaching a plateau, indicating that biodegradation might have proceeded further as the test continued; 7 Test not made; Tf2N− anion is known to be stable against degradation [183]; 8 Cabendazim, a fungicide compound, was employed as a positive control.