Table 2.
Bioactivity prediction for TBP and its analogs.
| Peptides | Peptide Ranker a | Anti-Inflammatory b | Antidiabetic c | Anti-Angiogenic d | Antihypertensive e | ||||
|---|---|---|---|---|---|---|---|---|---|
| Score | Score | Descriptor | Score | Descriptor | Score | Descriptor | Score | Descriptor | |
| TBP | 0.250852 | 0.403 | Medium Confidence AIP | 257.92 | non-DPPIV | −0.96 | Non-anti-angiogenic | −1.49 | Non-AHT |
| 2 | 0.282936 | 0.424 | Medium Confidence AIP | 275.54 | non-DPPIV | −0.64 | Non-anti-angiogenic | −1.66 | Non-AHT |
| 3 | 0.146123 | 0.366 | Low Confidence AIP | 243.08 | non-DPPIV | −1.18 | Non-anti-angiogenic | −1.89 | Non-AHT |
| 4 | 0.318239 | 0.435 | Medium Confidence AIP | 254.08 | non-DPPIV | −0.62 | Non-anti-angiogenic | −1.87 | Non-AHT |
| 5 | 0.301595 | 0.412 | Medium Confidence AIP | 252.77 | non-DPPIV | −0.52 | Non-anti-angiogenic | −1.6 | Non-AHT |
| 6 | 0.341132 | 0.415 | Medium Confidence AIP | 250.92 | non-DPPIV | −0.98 | Non-anti-angiogenic | −2.18 | Non-AHT |
| 7 | 0.29307 | 0.43 | Medium Confidence AIP | 271.15 | non-DPPIV | −1.15 | Non-anti-angiogenic | −1.96 | Non-AHT |
| 8 | 0.581973 | 0.611 | High Confidence AIP | 250.92 | non-DPPIV | −0.57 | Non-anti-angiogenic | −0.1 | Non-AHT |
| 9 | 0.0930615 | 0.607 | High Confidence AIP | 156.15 | non-DPPIV | 1.8 | Anti-angiogenic | 0.04 | AHT |
| 10 | 0.38964 | 0.334 | negative AIP | 276.50 | non-DPPIV | −1.25 | Non-anti-angiogenic | −1.43 | Non-AHT |
| 11 | 0.21006 | 0.402 | Medium Confidence AIP | 250.15 | non-DPPIV | −1.02 | Non-anti-angiogenic | −1.42 | Non-AHT |
| 12 | 0.146824 | 0.359 | Low Confidence AIP | 238.46 | non-DPPIV | −1.68 | Non-anti-angiogenic | −1.62 | Non-AHT |
| 13 | 0.120407 | 0.362 | Low Confidence AIP | 230.69 | non-DPPIV | −1.52 | Non-anti-angiogenic | −1.34 | Non-AHT |
| 14 | 0.437794 | 0.421 | Medium Confidence AIP | 268.00 | non-DPPIV | −0.29 | Non-anti-angiogenic | −1.15 | Non-AHT |
| 15 | 0.539862 | 0.477 | High Confidence AIP | 286.00 | non-DPPIV | −0.83 | Non-anti-angiogenic | −1.41 | Non-AHT |
| 16 | 0.751235 | 0.493 | High Confidence AIP | 296.08 | DPPIV | −0.11 | Non-anti-angiogenic | −0.95 | Non-AHT |
| 17 | 0.322171 | 0.403 | Medium Confidence AIP | 273.38 | non-DPPIV | −0.96 | Non-anti-angiogenic | −1.57 | Non-AHT |
| 18 | 0.225945 | 0.416 | Medium Confidence AIP | 248.77 | non-DPPIV | −1.44 | Non-anti-angiogenic | −2.16 | Non-AHT |
| 19 | 0.279449 | 0.419 | Medium Confidence AIP | 264.23 | non-DPPIV | −1.29 | Non-anti-angiogenic | −1.96 | Non-AHT |
| 20 | 0.280885 | 0.404 | Medium Confidence AIP | 255.08 | non-DPPIV | −1.43 | Non-anti-angiogenic | −1.89 | Non-AHT |
| 21 | 0.279711 | 0.231 | negative AIP | 251.57 | non-DPPIV | −1.23 | Non-anti-angiogenic | −1.62 | Non-AHT |
| 22 | 0.384437 | 0.512 | High Confidence AIP | 241.25 | non-DPPIV | −1.37 | Non-anti-angiogenic | −1.46 | Non-AHT |
| 23 | 0.492159 | 0.476 | High Confidence AIP | 233.22 | non-DPPIV | −1.15 | Non-anti-angiogenic | −1.02 | Non-AHT |
| 24 | 0.477331 | 0.441 | Medium Confidence AIP | 233.22 | non-DPPIV | −1.11 | Non-anti-angiogenic | −0.22 | Non-AHT |
| 25 | 0.255879 | 0.524 | High Confidence AIP | 229.13 | non-DPPIV | −0.64 | Non-anti-angiogenic | −1.82 | Non-AHT |
| 26 | 0.131233 | 0.311 | negative AIP | 232.21 | non-DPPIV | −0.29 | Non-anti-angiogenic | −1.43 | Non-AHT |
| 27 | 0.194823 | 0.244 | negative AIP | 253.86 | non-DPPIV | −1.21 | Non-anti-angiogenic | −1.8 | Non-AHT |
| 28 | 0.227495 | 0.245 | negative AIP | 268.21 | non-DPPIV | −1.09 | Non-anti-angiogenic | −1.62 | Non-AHT |
| 29 | 0.509724 | 0.541 | High Confidence AIP | 299.67 | DPPIV | 1.01 | Anti-angiogenic | −0.31 | Non-AHT |
| 30 | 0.310984 | 0.423 | Medium Confidence AIP | 274.67 | non-DPPIV | −1.35 | Non-anti-angiogenic | −1.6 | Non-AHT |
| 31 | 0.598761 | 0.57 | High Confidence AIP | 231.27 | non-DPPIV | 0.64 | Anti-angiogenic | −1.19 | Non-AHT |
| 32 | 0.345985 | 0.388 | Low Confidence AIP | 294.85 | DPPIV | −0.68 | Non-anti-angiogenic | −0.68 | Non-AHT |
| 33 | 0.444989 | 0.408 | Medium Confidence AIP | 307.15 | DPPIV | −0.6 | Non-anti-angiogenic | −0.09 | Non-AHT |
ahttp://distilldeep.ucd.ie/PeptideRanker/ (accessed on 2 February 2021). b http://kurata14.bio.kyutech.ac.jp/PreAIP/ (accessed on 2 February 2021). c http://camt.pythonanywhere.com/iDPPIV-SCM (accessed on 2 February 2021). d https://webs.iiitd.edu.in/raghava/antiangiopred/ (accessed on 2 February 2021). e http://crdd.osdd.net/raghava/ahtpin/ (accessed on 2 February 2021).