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. 2021 Apr 3;26(7):2064. doi: 10.3390/molecules26072064

Table 4.

Tuna backbone peptide and its analogs.

Peptide Sequence Modifications from TBP Mol. Weight (g/mol) Isoelectric Point
TBP VKAGFAWTANQQLS 1520.71 10.1
2 VIAGFAWTANQQLS K(2) → I(2) 1505.69 6
3 VKAGFAITANQQLS W(7) → I(7) 1447.66 10.1
4 VKAGFAWIANQQLS T(8) → I(8) 1532.76 10.1
5 VKAGFAWTAIQQLS N(10) → I(10) 1519.76 10.1
6 VKAGFAWTANIQLS Q(11) → I(11) 1505.74 10.1
7 VKAGFAWTANQQLI S(14) → I(14) 1546.79 10.1
8 VIAGFAIIAIIILI Full Hydrophobic Peptide 1439.89 6
9 RKKRKRWTKNQQRS Full Hydrophilic Peptide 1900.22 13
10 VAGFAAL Full Hydrophobic Peptide 647.77 6
11 VKAGGAWTANQQLS F(5) → G(5) 1430.58 10.1
12 VKAGFAGTANQQLS W(7) → G(7) 1391.55 10.1
13 VKAGGAGTANQQLS F(5), W(7) → G(5,7) 1301.42 10.1
14 WKAGFAWTANQQLS V(1) → W(1) 1607.79 10.1
15 VKAGFAWTANQQLW S(14) → W(14) 1619.84 10.1
16 WKAGFAWTANQQLW V(1), S(14) → W(1,14) 1706.92 10.1
17 VDAGFAWTANQQLS K(2) → D(2) 1507.62 3.1
18 VKAGFAWTANDQLS Q(11) → D(11) 1507.67 6.8
19 VDAGFAWTANDQLS K(2), Q(11) → D(2,11) 1494.58 2.9
20 VDAGFAWTANDDLS K(2), Q(11), Q(12) → D(2,11,12) 1481.54 2.8
21 VKAGFAWGTANQQLS G(8) inserted 1577.76 10.1
22 VKAGFAWGGGTANQQLS G(8,9,10) inserted 1691.86 10.1
23 VKAGGGFAWGGGTANQQLS G(5,6,10,11,12) inserted 1805.97 10.1
24 VKAGGGFAWGGGTANGGQQ G(5,6,10,11,12,16,17) inserted, LS removed 1719.83 10.1
25 VKAGFAWTRKANQQLS R(9), K(10) inserted 1805.07 11.7
26 VKAGRAWTRANQQLS R(5), R(10) inserted 1685.91 12.5
27 VKAGFAWTDANQQLS D(9) inserted 1635.8 6.8
28 VDAGFAWTDANQQLS D(9) inserted, K(2) → D(2) 1622.71 2.9
29 VKAWFWTWNQQLS G(4), A(8) → W(4,8) 1693.93 10.1
30 VKAGFAWTANQQL S(14) removed 1433.63 10.1
31 CVKAGFAWTANQQLSC C(1,16) inserted 1727 8.3
32 VPAGFAWTANQQLS K(2) → P(2) 1489.65 6
33 VPAGFAWTANQPLS K(2), Q(12) → P(2,12) 1458.64 6