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. 2021 Apr 4;22(7):3752. doi: 10.3390/ijms22073752

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Association of the expression ZNF71 and its isoform with paclitaxel drug response (IC₅₀) in NSCLC cell lines (n = 75). ZNF71 KRAB expression was significantly higher in paclitaxel-resistant cell lines compared with paclitaxel-sensitive cell lines. (A) Paclitaxel IC₅₀ values of NSCLC cell lines. (B–D) Comparison of ZNF71 overall (B), KRAB-less isoform (C), and KRAB isoform (D) expression in cell lines categorized by IC₅₀ values (resistant versus sensitive). ** p < 0.01 in two-sample t-tests used in (B–D).