Table A4.
Correlation of the expression of EMT markers and ZNF71 isoforms with immune scores and stromal scores quantified with ESTIMATE in NSCLC tumors (n = 197).
| Correlation with Immune Scores | Correlation with Stromal Scores | Partial Correlation with Immune Scores (Removing the Effect of Stromal Scores) |
Partial Correlation with Stromal Scores (Removing the Effect of Immune Scores) |
|
|---|---|---|---|---|
| ZEB1 | 0.13 | 0.55 *** | −0.235 *** | 0.573 *** |
| VIM | 0.21 ** | 0.3 *** | 0 | 0.447 *** |
| FN1 | 0.11 | 0.34 *** | −0.29 *** | 0.595 *** |
| CD24 | −0.23 ** | −0.2 ** | −0.175 * | 0.022 |
| CDH1 | −0.18 * | −0.12 | −0.157 * | −0.05 |
| CLDN7 | −0.12 | −0.12 | −0.07 | −0.079 |
| CTNNB1 | −0.083 | 0.041 | −0.189 ** | 0.19 ** |
| DDR1 | −0.38 *** | −0.36 *** | −0.29 *** | −0.137 |
| EPCAM | −0.24 *** | −0.25 *** | −0.167 * | −0.178 * |
| ESRP1 | −0.56 *** | −0.42 *** | −0.404 *** | −0.184 ** |
| ESRP2 | −0.32 ** | −0.25 *** | −0.117 | −0.159 * |
| KRT8 | −0.32 ** | −0.19 ** | −0.114 | −0.103 |
| KRT19 | −0.17 * | −0.28 *** | 0.043 | −0.089 |
| RAB25 | −0.25 *** | −0.26 *** | −0.151 * | −0.175 * |
| ZNF71 overall | −0.12 | −0.17 * | 0.015 | −0.059 |
| ZNF71 KRAB | −0.11 | −0.16 * | −0.157 | −0.055 |
| ZNF71 KRAB-less | −0.085 | −0.11 | −0.114 | 0.005 |
* p-value < 0.05, ** p-value < 0.01, and *** p-value < 0.001 in Pearson’s correlation tests or partial correlation tests