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EGFR mutation in sensitive or resistant NSCLC cell lines in response to treatment with gefitinib and erlotinib, respectively.
| Sensitive | Resistant | ||
|---|---|---|---|
| Gefitinib | IC50 | HCC4006, HCC827, LOUNH91, NCIH1355, NCIH1568 | HCC1359, NCIH1793, NCIH226, SKMES1 |
| EC50 | HCC4006, HCC827, NCIH1355, NCIH1568, NCIH1975, NCIH226, PC14 | HCC1359, SKMES1 | |
| Erlotinib | IC50 | HCC4006, HCC827, NCIH1355, NCIH1650, NCIH1793 | |
| EC50 | HCC1359, HCC4006, HCC827, NCIH1355, NCIH1650, NCIH1975, PC14 | NCIH226, SKMES1 | |
