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. 2021 Apr 3;22(7):3751. doi: 10.3390/ijms22073751
ASD autism spectrum disorder
AD Alzheimer’s disease
AMPA 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl) propanoic acid
AAV adeno-associated virus
BBB blood brain barrier
BDNF brain-derived neurotrophic factor
BRD4 bromodomain 4
CDKL5 cyclin dependent kinase like 5
CNS central nervous system
CTD C-terminal domain
EB embryoid bodies
E/I excitatory/inhibitory imbalance
EVs extracellular vesicles
FOXG1 forkhead box G1
FLT3 fms-like tyrosine kinase 3
GABA gamma-aminobutyric acid
GFAP glial fibrillary acidic protein
GluR2/3 glutamate receptor subunit
HDAC histone deacetylases
HDAC6 histone deacetylases 6
hESCs human embryonic stem cells
hiPSCs human induced pluripotent stem cells
Hsp heat-shock proteins
HTS high-throughput screening
HUVECs human umbilical vein endothelial cells
IC isogenic control
ID intervening domain
IGF-1 insulin-like growth factor-1
IL interleukin
ILVs intraluminal vesicles
INs interneurons
L1CAM L1 cell adhesion molecule
LPS lipopolysaccharides
MBD methyl-CpG binding domain
MEA multi electrode array
MeCP2 methyl-CpG-binding protein 2
MeCP2LOF methyl-CpG-binding protein 2 loss of function
MeCP2-KO methyl-CpG-binding protein 2 knocking out
MGE medial ganglionic eminence
miRNAs micro RNAs
mRNAs messenger RNA
mtDNA mitochondrial DNA
MVs microvesicles
MVBs multivesicular bodies
NCOR nuclear co-repressor
NMDA N-methyl-d-aspartate
NPs neural progenitors
NPCs neural progenitor cells
NTD N-terminal domain
OL oligodendrocytes
oRGCs outer radial glia cells
oSVZ outer subventricular zone
PSD-95 postsynaptic density protein 95
RG radial glia
rhIGF1 full-length recombinant human IGF1
RNA ribonucleic acid
RNA-seq ribonucleic acid sequencing
ROS reactive oxygen species
RTT Rett Syndrome
siRNA small interfering RNA
SMRT silencing mediator of retinoic acid and thyroid hormone receptor
STT somatostatin
TGF-β1 transforming growth factor beta 1
TRD transcriptional repression domain
TrkB tropomyosin-related kinase B
KCC2 neuron-specific K+-Cl cotransporter 2
XCI X-chromosome inactivation