| ASD | autism spectrum disorder |
| AD | Alzheimer’s disease |
| AMPA | 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl) propanoic acid |
| AAV | adeno-associated virus |
| BBB | blood brain barrier |
| BDNF | brain-derived neurotrophic factor |
| BRD4 | bromodomain 4 |
| CDKL5 | cyclin dependent kinase like 5 |
| CNS | central nervous system |
| CTD | C-terminal domain |
| EB | embryoid bodies |
| E/I | excitatory/inhibitory imbalance |
| EVs | extracellular vesicles |
| FOXG1 | forkhead box G1 |
| FLT3 | fms-like tyrosine kinase 3 |
| GABA | gamma-aminobutyric acid |
| GFAP | glial fibrillary acidic protein |
| GluR2/3 | glutamate receptor subunit |
| HDAC | histone deacetylases |
| HDAC6 | histone deacetylases 6 |
| hESCs | human embryonic stem cells |
| hiPSCs | human induced pluripotent stem cells |
| Hsp | heat-shock proteins |
| HTS | high-throughput screening |
| HUVECs | human umbilical vein endothelial cells |
| IC | isogenic control |
| ID | intervening domain |
| IGF-1 | insulin-like growth factor-1 |
| IL | interleukin |
| ILVs | intraluminal vesicles |
| INs | interneurons |
| L1CAM L1 | cell adhesion molecule |
| LPS | lipopolysaccharides |
| MBD | methyl-CpG binding domain |
| MEA | multi electrode array |
| MeCP2 | methyl-CpG-binding protein 2 |
| MeCP2LOF | methyl-CpG-binding protein 2 loss of function |
| MeCP2-KO | methyl-CpG-binding protein 2 knocking out |
| MGE | medial ganglionic eminence |
| miRNAs | micro RNAs |
| mRNAs | messenger RNA |
| mtDNA | mitochondrial DNA |
| MVs | microvesicles |
| MVBs | multivesicular bodies |
| NCOR | nuclear co-repressor |
| NMDA | N-methyl-d-aspartate |
| NPs | neural progenitors |
| NPCs | neural progenitor cells |
| NTD | N-terminal domain |
| OL | oligodendrocytes |
| oRGCs | outer radial glia cells |
| oSVZ | outer subventricular zone |
| PSD-95 | postsynaptic density protein 95 |
| RG | radial glia |
| rhIGF1 | full-length recombinant human IGF1 |
| RNA | ribonucleic acid |
| RNA-seq | ribonucleic acid sequencing |
| ROS | reactive oxygen species |
| RTT | Rett Syndrome |
| siRNA | small interfering RNA |
| SMRT | silencing mediator of retinoic acid and thyroid hormone receptor |
| STT | somatostatin |
| TGF-β1 | transforming growth factor beta 1 |
| TRD | transcriptional repression domain |
| TrkB | tropomyosin-related kinase B |
| KCC2 | neuron-specific K+-Cl− cotransporter 2 |
| XCI | X-chromosome inactivation |