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. 2021 Apr 3;22(7):3750. doi: 10.3390/ijms22073750

Figure 3.

Figure 3

CHOP expression is upregulated at the transcriptional level in ZIKV infected cells. (a): qRT-PCR analysis of CHOP mRNA was performed in A549 cells harvested 24 h after being infected with ZIKV at different MOI (1, 5 and 10). CHOP mRNA expression was normalized to the GAPDH mRNA level. Data were presented as mean SEM (n = 3). **** p < 0.0001, *** p < 0.001 vs. mock. (b): qRT-PCR analysis of CHOP mRNA was performed in A549 cells harvested at 24 h and 48 h after being infected or not with ZIKV at MOI 5 and MOI 10 or treated with TG for 6 h. CHOP mRNA expression was normalized to the GAPDH mRNA level. Data were presented as mean and SEM (n = 3). *** p < 0.001, ** p < 0.01 vs. mock.