Figure 14.
Upregulation of key Sonic Hedgehog (SHH) pathway genes SHH, PTCH1, SMO, and GLI1 in both BE and EAC cells. qRT-PCR of BE and EAC cell lines vs. primary NE (HEEpiC) cells revealed that RNA expression levels of the key SHH pathway genes SHH, PTCH1, SMO, and GLI1 were upregulated in both BE (CP-C and CP-A) cell lines and in all four EAC (FLO-1, JH-EsoAd1, OE33, and SKGT4) cell lines studied.
