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Upregulation of SHH and inverse correlation of miR205HG and SHH expression levels in BE tissues. Tissues from 14 patients with BE were tested by qRT-PCR. SHH was significantly upregulated relative to NE in all BE tissues studied (14/14, average fold-change 2913.0, paired t-test p-value < 0.0001). In addition, miR205HG and SHH expression levels were inversely correlated (r = −0.83, p-value = 0.0004).
