Table 2.
List of downregulated genes with fold change > 1.3 compared to control group.
| Gene Symbol | Description | Fold Change | p-Value |
|---|---|---|---|
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | −3.13 | 0.0017 |
| ZC3H11A | zinc finger CCCH-type containing 11A | −2.82 | 0.0272 |
| CCDC186 | coiled-coil domain containing 186 | −2.73 | 0.0399 |
| PRDM2 | PR domain containing 2, with ZNF domain | −2.61 | 0.0239 |
| SPAG9 | Sperm-associated antigen 9 | −2.43 | 0.0137 |
| RBAK | RB-associated KRAB zinc finger | −2.41 | 0.0466 |
| PRRC2C | proline-rich coiled-coil 2C | −2.4 | 0.0454 |
| BOD1L1 | biorientation of chromosomes in cell division 1-like 1 | −2.29 | 0.0345 |
| BAZ1B | bromodomain adjacent to zinc finger domain 1B | −2.26 | 0.0306 |
| ALG11 | ALG11, alpha-1,2-mannosyltransferase | −2.25 | 0.0111 |
| ZNF480 | zinc finger protein 480 | −2.22 | 0.0477 |
| RNPC3 | RNA binding region (RNP1, RRM) containing 3 | −2.18 | 0.0064 |
| MIER1 | mesoderm induction early response 1, transcriptional regulator | −2.13 | 0.011 |
| PDE4DIP | phosphodiesterase 4D interacting protein | −2.08 | 0.0478 |
| USP1 | ubiquitin specific peptidase 1 | −2.08 | 0.0315 |
| GCC2 | GRIP and coiled-coil domain containing 2 | −2.06 | 0.0378 |
| TCERG1 | transcription elongation regulator 1 | −2.06 | 0.0152 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | −2.05 | 0.0491 |
| LMAN1 | lectin, mannose-binding, 1 | −2.02 | 0.0137 |
| CEP57 | centrosomal protein 57 kDa | −2.01 | 0.0241 |
| NBPF10 | neuroblastoma breakpoint family, member 10 | −1.99 | 0.0261 |
| WASL | Wiskott–Aldrich syndrome-like | −1.99 | 0.0414 |
| WHSC1L1 | Wolf–Hirschhorn syndrome candidate 1-like 1 | −1.99 | 0.0163 |
| SWAP70 | SWAP switching B-cell complex 70 kDa subunit | −1.95 | 0.0452 |
| EFCAB14 | EF-hand calcium binding domain 14 | −1.9 | 0.0187 |
| EIF4G1 | eukaryotic translation initiation factor 4 gamma, 1 | −1.88 | 0.0381 |
| KMT2C | lysine (K)-specific methyltransferase 2C | −1.87 | 0.0496 |
| TNKS2 | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 | −1.86 | 0.0056 |
| IL6ST | interleukin 6 signal transducer | −1.84 | 0.0118 |
| SON | SON DNA binding protein | −1.8 | 0.0463 |
| FAM107B | family with sequence similarity 107, member B | −1.78 | 0.0437 |
| SF3B1 | splicing factor 3b, subunit 1, 155 kDa | −1.76 | 0.0248 |
| OTUD4 | OTU deubiquitinase 4 | −1.75 | 0.0445 |
| PPIG | peptidylprolyl isomerase G (cyclophilin G) | −1.75 | 0.0348 |
| PEG10 | paternally expressed 10 | −1.71 | 0.0298 |
| CBX5 | chromobox homolog 5 | −1.69 | 0.0143 |
| KMT2A | lysine (K)-specific methyltransferase 2A | −1.68 | 0.0378 |
| ANKRD12 | ankyrin repeat domain 12 | −1.63 | 0.0372 |
| AP3M2 | adaptor-related protein complex 3, mu 2 subunit | −1.62 | 0.0284 |
| REST | RE1-silencing transcription factor | −1.62 | 0.0308 |
| WAC | WW domain containing adaptor with coiled-coil | −1.62 | 0.0225 |
| CTDSPL2 | CTD small phosphatase like 2 | −1.61 | 0.0333 |
| DNAJB14 | DnaJ (Hsp40) homolog, subfamily B, member 14 | −1.6 | 0.0244 |
| ZNF208 | zinc finger protein 208 | −1.59 | 0.0076 |
| CRCP | CGRP receptor component | −1.58 | 0.0169 |
| MLLT4 | myeloid/lymphoid or mixed-lineage leukemia; translocated to, 4 | −1.58 | 0.0077 |
| PCM1 | pericentriolar material 1 | −1.57 | 0.0419 |
| MBNL2 | muscleblind-like splicing regulator 2 | −1.55 | 0.0136 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | −1.53 | 0.0383 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | −1.53 | 0.044 |
| MCFD2 | multiple coagulation factor deficiency 2 | −1.53 | 0.0194 |
| SMC1A | structural maintenance of chromosomes 1A | −1.52 | 0.0205 |
| SMC5 | structural maintenance of chromosomes 5 | −1.52 | 0.0407 |
| GOLGA2 | golgin A2 | −1.51 | 0.0456 |
| LRP10 | LDL receptor-related protein 10 | −1.51 | 0.0223 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | −1.51 | 0.0303 |
| SKI | SKI proto-oncogene | −1.5 | 0.0161 |
| SPIN1 | spindlin 1 | −1.5 | 0.0389 |
| LGALSL | lectin, galactoside-binding-like | −1.49 | 0.0259 |
| MYH11 | myosin, heavy chain 11, smooth muscle | −1.49 | 0.0071 |
| TBC1D23 | TBC1 domain family, member 23 | −1.49 | 0.0272 |
| DYM | dymeclin | −1.48 | 0.027 |
| GAPVD1 | GTPase-activating protein and VPS9 domains 1 | −1.48 | 0.0319 |
| PGAM5 | PGAM family member 5, serine/threonine protein phosphatase, mitochondrial | −1.47 | 0.0211 |
| SUPT20H | SPT20 homolog, SAGA complex component | −1.47 | 0.039 |
| MGA | MGA, MAX dimerization protein | −1.46 | 0.0043 |
| SGMS2 | sphingomyelin synthase 2 | −1.46 | 0.0256 |
| ZNF91 | zinc finger protein 91 | −1.46 | 0.0258 |
| PAPOLA | poly(A) polymerase alpha | −1.45 | 0.0277 |
| PHF24 | PHD finger protein 24 | −1.45 | 0.039 |
| CNOT4 | CCR4-NOT transcription complex subunit 4 | −1.44 | 0.0162 |
| KTN1 | kinectin 1 (kinesin receptor) | −1.43 | 0.0406 |
| MAP4K5 | mitogen-activated protein kinase 5 | −1.43 | 0.0129 |
| ZNF766 | zinc finger protein 766 | −1.43 | 0.0093 |
| CDK12 | cyclin-dependent kinase 12 | −1.42 | 0.0343 |
| ITGAD | integrin alpha D | −1.41 | 0.0217 |
| MGEA5 | meningioma expressed antigen 5 (hyaluronidase) | −1.41 | 0.0036 |
| ATF6 | activating transcription factor 6 | −1.4 | 0.0175 |
| DNASE1 | deoxyribonuclease I | −1.4 | 0.024 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A | −1.39 | 0.0491 |
| RAB11FIP1 | RAB11 family interacting protein 1 (class I) | −1.39 | 0.0298 |
| DDR2 | discoidin domain receptor tyrosine kinase 2 | −1.38 | 0.0287 |
| EPRS | glutamyl-prolyl-tRNA synthetase | −1.38 | 0.0102 |
| HN1L | hematological and neurological expressed 1-like | −1.38 | 0.0201 |
| MEI1 | meiotic double-stranded break formation protein 1 | −1.38 | 0.043 |
| PAPD5 | PAP-associated domain containing 5 | −1.38 | 0.0489 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | −1.38 | 0.0064 |
| UBE2J1 | ubiquitin-conjugating enzyme E2, J1 | −1.38 | 0.0219 |
| UBXN4 | UBX domain protein 4 | −1.38 | 0.0492 |
| CCDC50 | coiled-coil domain containing 50 | −1.37 | 0.0247 |
| GCK | glucokinase (hexokinase 4) | −1.37 | 0.0178 |
| PLA2G5 | phospholipase A2, group V | −1.37 | 0.01 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | −1.37 | 0.0491 |
| ARHGAP35 | Rho GTPase activating protein 35 | −1.36 | 0.0299 |
| PRKAR2A | protein kinase, cAMP-dependent, regulatory, type II, alpha | −1.35 | 0.0455 |
| TLK1 | tousled-like kinase 1 | −1.35 | 0.0076 |
| AFF1 | AF4/FMR2 family, member 1 | −1.34 | 0.0214 |
| LINC00303 | long intergenic non-protein coding RNA 303 | −1.34 | 0.0341 |
| OR5AK2 | olfactory receptor, family 5, subfamily AK, member 2 | −1.34 | 0.0287 |
| PCLO | piccolo presynaptic cytomatrix protein | −1.34 | 0.0089 |
| CCDC30 | coiled-coil domain containing 30 | −1.33 | 0.0115 |
| CDC40 | cell division cycle 40 | −1.33 | 0.0303 |
| DNAJB5 | DnaJ (Hsp40) homolog, subfamily B, member 5 | −1.33 | 0.0228 |
| RMI1 | RecQ mediated genome instability 1 | −1.33 | 0.0495 |
| SLC25A36 | solute carrier family 25 (pyrimidine nucleotide carrier), member 36 | −1.33 | 0.0231 |
| ZNF215 | zinc finger protein 215 | −1.33 | 0.0353 |
| MAGEC3 | MAGE family member C3 | −1.32 | 0.0298 |
| SLC35E4 | solute carrier family 35, member E4 | −1.32 | 0.0151 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | −1.31 | 0.0405 |
| FAM120A | family with sequence similarity 120A | −1.31 | 0.0195 |
| FAM208B | family with sequence similarity 208, member B | −1.31 | 0.0302 |
| KATNBL1 | katanin p80 subunit B-like 1 | −1.31 | 0.049 |
| MFSD12 | major facilitator superfamily domain containing 12 | −1.31 | 0.0399 |
| MT1A | metallothionein 1A | −1.31 | 0.0471 |
| ZNF609 | zinc finger protein 609 | −1.31 | 0.0383 |
| ZNF750 | zinc finger protein 750 | −1.31 | 0.0259 |
| HLA-DOA | major histocompatibility complex, class II, DO alpha | −1.3 | 0.0497 |
| KCNE4 | potassium channel, voltage gated subfamily E regulatory beta subunit 4 | −1.3 | 0.0429 |
| LINC00656 | long intergenic non-protein coding RNA 656 | −1.3 | 0.0252 |
| LINC01118 | long intergenic non-protein coding RNA 1118 | −1.3 | 0.0228 |
| OR1M1 | olfactory receptor, family 1, subfamily M, member 1 | −1.3 | 0.0127 |
| OSBPL8 | oxysterol binding protein-like 8 | −1.3 | 0.0323 |
| RPAP2 | RNA polymerase II-associated protein 2 | −1.3 | 0.0153 |
| ZNF257 | zinc finger protein 257 | −1.3 | 0.0266 |