Table 1.

Clinical biochemistry profile and endothelial function parameters in controls and breast cancer patients.

Parameter	Control (n = 18)	HR+ HER2+ (n = 12)	HR+ HER2- (n = 16)	TNBC (n = 19)
CRPhs, mg/dL	0.37 ± 0.05	0.34 ± 0.02	0.44 ± 0.04	0.38 ± 0.08
LDL, mg/dL	109 ± 10.2	120 ± 21.8	105 ± 6.57	130 ± 17
HDL, mg/dL	65.4 ± 5.82	54.6 ± 5.82	55.4 ± 4.77	41.2 ± 5.82 *
CHOL, mg/dL	199 ± 13.8	201 ± 17.6	195.3 ± 9.80	204.3 ± 20.5
TG, mg/dL	123 ± 18.9	116 ± 18.4	173 ± 32.8	164.3 ± 15.44
ALB, g/dL	4.75 ± 0.12	4.09 ± 0.50	4.80 ± 0.32	4.20 ± 0.19
Total protein, g/dL	8.23 ± 0.34	6.44 ± 1.25	6.60 ± 0.5	7.36 ± 0.30
ALP, U/L	59.7 ± 10.1	43.7 ± 4.24	63.6 ± 11.2	64.6 ± 12.08
Ca, mg/dL	13.6 ± 4.00	9.92 ± 1.27	9.69 ± 0.87	11.3 ± 1.57
LDH, U/L	353 ± 21.3	358 ± 29.9	425 ± 23.5	406 ± 21.2
Mg, mg/dL	2.90 ± 0.55	2.14 ± 0.54	2.17 ± 0.33	2.45 ± 0.40
Pho, mg/dL	4.06 ± 0.20	3.9 ± 0.23	4.47 ± 0.40	3.95 ± 0.10
AST, U/L	22.3 ± 1.88	18.34 ± 2.37	23.49 ± 1.90	24.5 ± 3.57
ALT, U/L	21.6 ± 2.85	18.0 ± 4.00	19.29 ± 2.24	18.55 ± 2.17
Urea, mg/dL	30.4 ± 1.52	28.3 ± 2.58	38.2 ± 3.02	27.23 ± 3.29
ADMA, μmol/L	0.73 ± 0.08	0.93 ± 0.1	0.97 ± 0.09	1.23 ± 0.14 **
ADMA/L-arginine ratio	0.017 ± 0.002	0.021 ± 0.005	0.022 ± 0.002	0.026 ± 0.003

Results are shown as mean ± SEM, * p < 0.05, ** p < 0.01 vs. control. CRPhs, high-sensitive C-reactive protein; LDL, low density lipoproteins; HDL, high density lipoproteins; CHOL, total cholesterol; TG, triglycerides; ALB, albumin; Ca, calcium; ALP, alkaline phosphatase; LDH, lactate dehydrogenase; Mg, Magnesium; Pho, Phosphorus; AST, aspartate transaminase; ALT, alanine transaminase, ADMA, asymmetric dimethylarginine. * p < 0.05, ** p < 0.01 vs. control by one-way ANOVA followed by Holm-Sidak post hoc test.