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Roles of DDRs in the mechanism of EMT.
| Receptor | EMT | Cancers |
|---|---|---|
| DDR1 | Increase | -Prostate [101] -Gastric [102,103] -Hepatocellular carcinoma [35] -Colorectal [84] -Renal carcinoma [85] |
| Decrease | -Breast carcinoma [31,104,105] -Ovarian [45,104] -Liver (female, [104]) |
|
| DDR2 | Increase | -Breast [30,90,98] -Ovarian [32] -Papillary thyroid carcinoma [107] -Hepatocellular carcinoma [89] -Gastric [67] |
| Decrease |
