Table 4.

Roles of DDRs in tumor cell migration and/or invasion.

Receptor	Migration/Invasion	Cancers
DDR1	Increase	-Squamous cell carcinoma [25,112] -Hepatocellular carcinoma [35] -Pancreatic [86] -Breast [113] -Renal carcinoma [85] -Gastric [103] -Prostate [53] -Colorectal [120] -Epidermoid carcinoma [48]
	Decrease	-Breast [118] -Pancreatic [114]
DDR2	Increase	-Gastric [64] -Hepatocellular carcinoma [65] -Melanoma [115] -Squamous cell carcinoma [63,116] -Breast [99,117] -Ovarian [32]
	Decrease