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. 2021 Apr 6;26(7):2086. doi: 10.3390/molecules26072086

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Anandamide (AEA) and 2-arachidonoylglycerol (2-AG) contents, fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAG-L) levels in the dorsal hippocampus (HC) after mSPS/Control or Air/CIE exposures. (A) Schematic of coronal slice where dorsal HC tissue punches were taken bilaterally (adapted from [58]). Average (B) AEA content (Control-Air: n = 6; Control CIE: n = 7; mSPS-Air: n = 6; mSPS-CIE: n = 8) increased in Control-CIE mice compared to Control-Air, mSPS-Air, or mSPS-CIE mice after mSPS/Control or Air/CIE exposures (* p < 0.05). However, the average (C) FAAH levels (Control-Air: n = 6; Control CIE: n = 4; mSPS-Air: n = 5; mSPS-CIE: n = 8) (Inset: representative immunoblotting sample images) did not change among groups after mSPS/Control or Air/CIE exposures. In addition, average (D) 2-AG (Control-Air: n = 6; Control CIE: n = 7; mSPS-Air: n = 6; mSPS-CIE: n = 8) and (E) MAG-L levels (Control-Air: n = 6; Control CIE: n = 4; mSPS-Air: n = 5; mSPS-CIE: n = 8) (Inset: representative immunoblotting sample images) did not change among groups after mSPS/Control or Air/CIE exposures. Data are mean ± SEM.