Table 1.
Inflammatory markers in polycystic ovary syndrome (PCOS) patients.
| Authors Ref. | Year of Publication | Study Design | Main Findings |
|---|---|---|---|
| Kelly, C.C., Lyall, H., Petrie, J.R. et al. [14] | 2001 | Clinical study | elevated CRP concentration in PCOS patients versus control group |
| Orio, F., Palomba, S., Casella, T. et al. [17] | 2005 | Clinical study | elevated CRP and WBC concentration in PCOS patients versus control group |
| Souza Dos Santos A.C., Soares, N.P. et al. [16] | 2015 | Clinical study | elevated CRP concentration in PCOS patients versus control group |
| Tola, E.N., Yalcin, S.E., Dugan, N. [15] | 2017 | Clinical study | elevated CRP concentration in PCOS patients versus control group WBC-distributed homogenously between PCOS and control group |
| Rudnicka, E., Kunicki, M., Suchta, K. et al. [10] | 2020 | Clinical study | elevated CRP and WBC concentration in PCOS patients versus control group |
| Escobar Morreale H.F., Laque-Ramirez, M., Gonzalez, F. [18] | 2011 | Systematic review and meta-analysis | elevated CRP concentration in PCOS patients versus control group, no statistically significant difference in IL-6 and TNF-αin PCOS patients versus control group |
| Toulis, K.A., Goulis, D.G., Mintziori, G. et al. [19] | 2011 | Systematic review and meta-analysis | elevated CRP concentration in PCOS patients versus control group no statistically significant difference in IL-6 and TNF-αin PCOS patients versus control group |
| Kaya, C., Pabuccu, R., Berker, B. et al. [22] | 2010 | Clinical study | elevated IL-18 concentration in PCOS patients versus control group |
| Escobar-Morreale, H.F., Botella-Carretero, J., Villuendas, G. et al. [23] | 2004 | Clinical study | elevated IL-18 concentration in PCOS patients versus control group |
| Glintborg, D., Andresen, M., Richelsen, B. et al. [24] | 2009 | Clinical study | elevated MCP-1 concentration in PCOS patients versus control group |
| Franik, G., Sadlocha, M., Madej, P. et al. [12] | 2020 | Clinical study | decreased concentration of omentin -1 levels in PCOS patients versus control group |
| Hu, W., Qiao, J., Yang, Y. et al. [25] | 2011 | Clinical study | elevated CRP and MCP-1 concentration in PCOS patients versus control group |
| Papolou, O., Livadas, S., Karachalios, A. et al. [36] | 2015 | Clinical study | elevated WBC concentration in PCOS patients versus control group |
| Herlihy, A.C., Kelly, R.E., Hogan, J.L. et al. [37] | 2011 | Clinical study | elevated WBC concentration in PCOS patients versus control group |
| Phelan, N., O’Connor, A., Tun, K. et al. [38] | 2013 | Clinical study | elevated WBC concentration in PCOS patients versus control group |
| Garg, D., Merhi, Z. [41] | 2016 | Clinical study | elevated AGEs concentration in PCOS patients versus control group |
| Merhi, Z. [42] | 2014 | Review | elevated AGEs concentration in PCOS patients versus control group |
| Diamanti-Kandarakis, E., Piperi, C., Kalofoutis, A. et al. [43] | 2005 | Clinical study | elevated AGEs and RAGE concentration in PCOS patients versus control group |
| Zhang, J., Bao, Y., Zhou, X. et al. [47] | 2019 | Review | mitochondrial dysfunction plays a role in pathogenesis of PCOS by increasing ROS and oxidative stress |
| Cozzolino, M., Seli, E. [48] | 2020 | Review | mitochondrial dysfunction plays a role in pathogenesis of PCOS by increasing ROS and oxidative stress |
| Uysal, S., Isik, A.Z., Eris, S. et al. [49] | 2015 | Clinical study | decreased endometrial glycodelin (induce apoptosis of monocytes) expression in PCOS women with miscarriage |