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. 2021 Apr 6;13(7):1743. doi: 10.3390/cancers13071743
mAb monoclonal antibodies
CD Cluster of differentiation
TAM tumor-associated macrophages
MDSC myeloid-derived suppressor cells
TME tumor microenvironment
APM antigen presenting machinery
MHC major histocompatibility complex
TGF-β transforming growth factor-β
IL interleukin
Arg arginase
MSC mesenchymal stem/stromal cells
CAF cancer-associated fibroblasts
EMT endothelial-to-mesenchymal transition
CXCL12 C-X-C Motif Chemokine Ligand 12
α-SMA α-smooth muscle actin
VEGF Vascular endothelial growth factor
STAT signal transducer and activator of transcription
ERK extracellular regulated kinase
CCL2 C-C Motif Chemokine Ligand 2
PGE2 prostaglandin E 2
Tregs Regulatory T cells
APC antigen-presenting cells
HIF1α hypoxia inducible factor 1α
LPS lipopolysaccharide
IFN-γ interferon gamma
MMP9 matrix metalloproteinase 9
TLR toll-like receptor
M-MDSC mononuclear MDSC
PMN-MDSC granulocytic or polymorphonuclear MDSC
eMDSC early-stage MDSC
LOX1 lectin-type oxidized low-density lipoprotein receptor 1
iNOS inducible nitric oxide synthase
PDGF Platelet-derived growth factor
IDO indoleamine 2,3-dioxygenase
MET mesenchymal-to-epithelial transition
SDF1 stromal cell-derived factor 1
HSC hematopoietic stem cells
CMP common myeloid progenitor cells
G-CSF granulocyte colony-stimulating factor
GM-CSF granulocyte-macrophage colony-stimulating factor
IRF8 Interferon regulatory factor 8
RAGE receptor for advanced glycation end products
TCR T cell receptor
ROS reactive oxygen species
RNS reactive nitrogen species
NO nitric oxide
PNT peroxynitrite
HDAC histone deacetylase
ATRA all-trans retinoic acid