Table 1.
Effect of SIT on body weight changes in adult male rats fed with high fat and sucrose-induced for 8weeks.β-sitosterol controlled body weight gain and ameliorated obesity.
| Duration | GROUP I Control (Weight in Grams) |
GROUP II Diabetes (Weight in Grams) |
GROUP III Diab + β-Sitosterol (Weight in Grams) |
GROUP IV Diab + Metformin (Weight in Grams) |
GROUP V Control + β-Sitosterol (Weight in Grams) |
|---|---|---|---|---|---|
| Initial | 185.5 ± 5.32 | 192.5 ± 6.74 | 195.4 ± 9.23 a | 189.5 ± 6.72 | 201.3 ± 6.62 a |
| 2nd week | 192.2 ± 7.45 1 | 220.3 ± 8.55 1, a | 210.3 ± 10.56 1, a, b | 206.2 ± 8.62 1, b | 200.5 ± 7.75 b |
| 4th week | 203.5 ± 8.25 1 | 230.2 ± 9.23 1, a | 215.3 ± 8.56 1, a, b | 210.3 ± 9.23 1, b | 209.3 ± 8.45 b |
| 6th week | 209.3 ± 6.78 1,2 | 270.5 ± 6.62 1,2,3, a, b | 225.2 ± 6.56 1,2,3, a, b | 220.5 ± 10.56 1,2,3, a, b | 215.4 ± 12.67 1,2,3, b, c |
| 8th week | 210.5 ± 5.78 1,2 | 310.4 ± 7.82 1,2,3,4, a, b | 230.3 ± 7.8 1,2,3,4, a, b | 210.3 ± 11.21 1,2,3,4, a, b, c | 195.5 ± 8.56 1,2,3,4, a, b, c |
Each value represents mean ± Standard Error of Mean (SEM) (n = 6). Significance at p < 0.05, a significantly different from the control group, b significantly different from the diabetic group and c significantly different from the β-sitosterol treated diabetic group. 1 significantly different from the initial body weight, 2 significantly different from the 2nd week, 3 significantly different from the 4th week and 4 significantly different from the 6th week.