Table 3.
Proteinuric findings in association with ARRS in ANCA GN.
| ARRS | Parameter | p Value |
|---|---|---|
| uPCR | ||
| High risk—mg/g | 5264 (1959–7426) | |
| Medium risk—mg/g | 977 (627–1743) | |
| Low risk—mg/g | 573 (359–1201) | <0.0001 |
| uACR | ||
| High risk—mg/g | 2946 (996–4223) | |
| Medium risk—mg/g | 470/314–839) | |
| Low risk—mg/g | 227 (86.1–504) | 0.0003 |
| Urinary IgG | ||
| High risk—mg/g | 261 (246–495) | |
| Medium risk—mg/g | 57.9 (30.8–159) | |
| Low risk—mg/g | 24.4 (13.3–37.3) | <0.0001 |
| Urinary α1-microglobulin | ||
| High risk—mg/g | 174 (116–280) | |
| Medium risk—mg/g | 92.3 (47.1–204) | |
| Low risk—mg/g | 37.1 (6.24–82.9) | 0.0009 |
| Urinary α2-macroglobulin | ||
| High risk—mg/g | 15.7 (8.29–28.2) | |
| Medium risk—mg/g | 5.06 (3.06–11.1) | |
| Low risk—mg/g | 3.33 (2.09–6.27) | 0.001 |
Median values and IQR are shown. Nonparametric Kruskal–Wallis test was applied for group comparisons. Abbreviations: ANCA, antineutrophil cytoplasmic antibodies; ARRS, ANCA renal risk score; GN, glomerulonephritis; IgG, immunoglobulin G; IQR, interquartile range; uACR, urinary albumin-to-creatinine ratio; uPCR, urinary protein-to-creatinine ratio.