Table 3.
Comparison of the expression difference of iTRAQ-identified serum proteins and oxidative stress markers between those patients with good outcomes (≥40 volume reduction in MR volumetry) and fair outcomes (<40% volume reduction in MR volumetry) following lymphaticovenous anastomosis.
| Good Outcome | Fair Outcome | p Value | |
|---|---|---|---|
| iTRAQ-identified protein | |||
| CAT, ng/mL | −2593 ± 2363 | 178 ± 603 | 0.021 |
| PRDX2, pg/mL | −7782 ± 7347 | −397 ± 1235 | 0.037 |
| CA1, IU/mL | 14 ± 175 | 126 ± 312 | 0.426 |
| CA2, pg/mL | 0.05 ± 0.04 | −0.03 ± 0.14 | 0.199 |
| Oxidative Stress Panel | |||
| TAC, umole/L | 21 ± 23 | 40 ± 39 | 0.406 |
| GPX, U/g | 12 ± 14 | 20 ± 25 | 0.557 |
| 8-OHdG, ng/mg | 4 ± 15 | 7 ± 19 | 0.799 |
| MPO, ng/mL | 9.0 ± 13 | 14 ± 45 | 0.833 |
CAT, catalase; PRDX2, peroxiredoxin-2; CA1, carbonic anhydrase 1; CA2, carbonic anhydrase 2; TAC, total antioxidant capacity; GPX, glutathione Peroxidase; 8-OHdG, 8-hydroxy-2′-deoxyguanosine; MPO, Myeloperoxidase; MR, magnetic resonance. Data are presented as post-LVA serum level minus pre-LVA serum level and expressed as mean ± standard deviation.