Table 3. Examples of B-cell neoplasm-associated possible spontaneous (idiopathic) cutaneous tumor lysis syndrome.

EBV, Epstein Barr virus; LG, lymphomatoid granulomatosis; LPD, lymphoproliferative disorder; Ref, reference; yo, year old

Patients	Tumor	Comments	Ref
56 yo man	Cutaneous B-cell lymphoma	A man presented with a rapidly growing tumor with satellite lesions of two-month duration on his upper back; the possible spontaneous (idiopathic) cutaneous tumor lysis manifested as skin necrosis with hemorrhage, suppuration, and ulceration of the 8 × 8-cm tumor mass	[31]
76 yo woman	Intravascular B-cell lymphoma	A woman’s lymphoma presented as possible spontaneous (idiopathic) cutaneous tumor lysis syndrome with two-month history of anorexia, fever, malaise, weight loss, and necrotic and crusted papules on her thighs	[32]
35 yo man	EBV- associated B-cell LPD	An immunocompetent man’s primary cutaneous, EBV-positive diffuse large B-cell lymphoma, not otherwise specified, presented with possible spontaneous (idiopathic) cutaneous tumor lysis; during the prior six months prior to medical evaluation, his lymphoma appeared as multiple, painful, and ulcerated nodules on his trunk and arms	[33]
Two of 20 patients	Cutaneous LG	At least two of 20 patients with cutaneous LG, an angiocentric and angiodestructive EBV-associated B-cell lymphoproliferative disorder, had lesions that were suggestive of spontaneous (idiopathic) cutaneous tumor lysis; their dermal and subcutaneous nodules have necrosis and central ulceration	[34]