Fig. 2.

Vancomycin clearance (in L/h) versus total body weight (in kg) for varying creatinine clearance values (CL_cr). Each dot represents one individual, with darker color representing a higher CL_cr. The lines show how clearance changes with body weight over the available weight range according to the final model for four typical values of CL_cr (i.e., 15, 50, 110, and 150 mL/min/1.73 m²), with corresponding CL_cr value shown in the figure for each line (mL/min/1.73 m²). CL_cr creatinine clearance based on the bedside Schwartz equation (in mL/min/1.73 m²)