Fig. 6.

Inverse regulation of steroidogenesis in P2P3 mice compared to P2H1 mice. a Gene expression analysis of enzymes involved in the steroidogenesis pathway in P2P3 mice and their WT counterparts (n = 12–13) was performed on mRNA from entire adrenal glands. All graphs represent pooled data from at least 3 independent experiments. b Relative expression profile of all genes analyzed from the adrenal glands of P2H1 and P2P3 mice and compared to their respective WT littermates. Statistical significance was defined using an unpaired multiple t test (n = 13; Benjamini, Krieger and Yekutieli method; *p < 0.0001 for all individual genes)