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. 2021 Feb 17;25(5):445–455. doi: 10.1007/s10157-021-02021-y

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — mRNA levels of major renal oxylipin enzymes in CKD kidney samples. Quantitative reverse transcription-polymerase chain reaction (qRT-PCR) analysis of major oxylipin enzymes expressed in the kidney (Alox15, Alox5, Ptgs1 [COX1], Ptgs2 [COX2], Cyp4a12 and Cyp2c44) was performed using sham and 5/6 nephrectomized (Nx) kidney samples. Compared with the sham kidneys, the 5/6 Nx kidneys had significantly increased mRNA level of Alox15 (P = 0.0004). The number of samples is shown at the bottom of the bar graph. Values are mean ± SEM. Unpaired Student’s t test, *P < 0.05