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. 2021 Feb 8;78(7):3637–3656. doi: 10.1007/s00018-021-03766-1

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© The Author(s) 2021, corrected publication 2021

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Fig. 5 — LecA induces clustering of PIP₃ in H1299 cells. a Left panel: time-lapse images of PH-Akt-GFP expressing H1299 cells exposed to fluorescent LecA over 60 min. On the left side, LecA binds two untransfected cells (traced in grey). Right panel: magnifications of framed areas highlight dynamic co-localizing events between LecA and PH-Akt-GFP correlating with LecA endocytosis (marked by blue arrows). Scale bar: 10 μm