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. 2020 Oct 16;159(4):1610–1620. doi: 10.1016/j.chest.2020.10.025

Table 2.

Multivariate Analysis of All Men

Model and Mortality LFCt Quartile HR (95% CI) P Value
Model 1 (n = 2,612)
 CV mortality 1 Reference
2 1.02 (0.76-1.37) .89
3 0.92 (0.68-1.23) .56
4 1.36 (1.02-1.81) .04
 All-cause mortality
1 Reference
2 1.02 (0.87-1.21) .78
3 0.98 (0.83-1.17) .86
4 1.35 (1.14-1.60) < .001
Model 2 (n = 2,580)
 CV mortality 1 Reference
2 1.00 (0.75-1.35) .97
3 0.89 (0.67-1.20) .46
4 1.36 (1.02-1.81) .04
 All-cause mortality
1 Reference
2 1.02 (0.86-1.21) .82
3 0.97 (0.82-1.14) .69
4 1.34 (1.13-1.59) < .001
Model 3 (n = 2,580)
 CV mortality 1 Reference
2 1.00 (0.75-1.35) .98
3 0.89 (0.66-1.20) .44
4 1.36 (1.02-1.81) .04
 All-cause mortality
1 Reference
2 1.02 (0.86-1.21) .85
3 0.96 (0.81-1.14) .66
4 1.35 (1.14-1.60) < .001

Cox proportional hazards regression models were used. Boldface indicates significant findings.

Model 1 adjusts for study site, race, age, BMI, smoking, alcohol use, diabetes, hypertension, coronary heart disease, heart failure, stroke, chronic obstructive lung disease, and chronic kidney disease.

Model 2 adjusts for model 1 covariates and apnea-hypopnea index.

Model 3 adjusts for model 2 covariates and time spent with oxygen saturation as measured by pulse oximetry < 90%.

CV = cardiovascular; HR = hazard ratio; LFCt = lung to finger circulation time.