Table 5.

Patient Hemodynamic, Functional, and Right Ventricular Characteristics at Baseline and 1-Year Follow-up, Stratified on Survival Time

	Survivors (N = 74)		Nonsurvivors
			≥ 5 Years (n = 20)		< 5 Years (n = 24)
	Baseline	FU	Baseline	FU	Baseline	FU
Functional
Age, y	48 ± 17		47 ± 14		54 ± 20
Sex, female, %	86		70		54
6MWD, m	450 ± 17	493 ± 18b	382 ± 28	449 ± 24	345 ± 44	418 ± 36
NT-proBNP, ng/L	586 [215-1,292]	138 [94-442]b	997 [266-3,136]	274 [106-1,597]	775 [439-2,950]	785 [143-1,881]
NYHA I/II/III/IV, %	8/44/46/3	26/67/8/0a	5/35/55/5	10/75/15/0	5/15/70/10	5/35/60/0
Hemodynamic
RHC-SVi, mL/m2	35 ± 2	47 ± 2b	29 ± 2	31 ± 2	29 ± 2	38 ± 3b
RAP, mm Hg	7 ± 0.4	5 ± 0.4a	10 ± 1.4	9 ± 1.1	10 ± 1.2	8 ± 1.2
RHC-CI, L/min/m2	2.7 ± 0.1	3.4 ± 0.1b	2.2 ± 0.1	2.5 ± 0.2	2.5 ± 0.2	3.2 ± 0.3c
RHC-PVRI, WU/m2	4.9 ± 0.3	2.7 ± 0.2b	5.7 ± 1.4	3.6 ± 1.0a	6.7 ± 0.8	4.1 ± 0.7b
RHC-Svo2, %	67 ± 1	71 ± 1b	61 ± 2	63 ± 2	59 ± 2	65 ± 2a
RHC-HR, beats/min	79 ± 2	75 ± 1a	79 ± 4	83 ± 3	89 ± 4	80 ± 3a
Imaging
CMR-SVi, mL/m2	30 ± 1	37 ± 1b	26 ± 2	29 ± 2	26 ± 2	30 ± 2
CMR-RVEF, %	38 ± 1	49 ± 1b	32 ± 2	33 ± 3	32 ± 2	37 ± 3
CMR-RVESVi, mL/m2	49 ± 2	40 ± 2b	59 ± 5	58 ± 5	55 ± 4	55 ± 5
CMR-RVEDVi, mL/m2	77 ± 2	76 ± 2	85 ± 5	84 ± 5	80 ± 4	84 ± 5

All comparisons are between baseline and follow-up measurements. P values are corrected for multiple comparisons. 6MWD = 6-min walk distance; CI = cardiac index; FU = follow-up; HR = heart rate; NT-proBNP = N-terminal pro-brain natriuretic peptide; NYHA = New York Heart Association; PVRi = pulmonary vascular resistance index; RAP = right atrial pressure; RHC = right heart catheterization; RVEDVi = right ventricular end-diastolic volume index; RVEF = right ventricular ejection fraction; RVESVi = right ventricular end-systolic volume index; SVi = stroke volume index; Svo₂ = mixed venous oxygen saturation; WU = Wood unit.

^aP < .05.

^bP < .001.

^cP < .01.