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. 2021 Apr 7;16:2667–2687. doi: 10.2147/IJN.S306831

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© 2021 Adel et al.

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Curcumin release profiles from spray-dried proliposomes formulations (SD/P) in ethanolic phosphate buffer solution (30% v/v; pH 7.4). The release profile of all the investigated formulations showed a distinctive biphasic release profile, where nearly more than 17.00% and less than 24.98% curcumin were released during the first 2 h followed by a sustained release pattern during the 48h testing period. All formulations released more than 95% curcumin at Q24h. No significant difference could be detected between investigated formulations in either Q2h or Q24h (P > 0.05).