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Different Lung Pharmacokinetic Parameters for Curcumin Powder and Curcumin Proliposomal Formulations
| Measured Parameter | Curcumin Powder | Improved SD/P4 | Improved SD/P6 |
|---|---|---|---|
| Tmax (h) | 2 | 1 | 1 |
| Cmax (ng/mL) | 1232.50 ± 247.57 | 5052.35 ± 1368.91 | 3345.75 ± 795.09 |
| AUC(0–24) (ng.h/mL) | 6908.69 ± 978.93 | 12.529.63 ± 1032.63 | 9936.73 ± 1368.68 |
| AUC(inf) (ng.h/mL) | 7193.12 ± 901.23 | 19.708.67 ± 4602.45 | 12.361.21 ± 2879.92 |
| MRT (h) | 4.80 ± 0.15 | 7.50 ± 0.17 | 7.30 ± 1.60 |
