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. 2021 Apr 7;13:3041–3053. doi: 10.2147/CMAR.S290088

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© 2021 Liang et al.

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Circ-OGDH promoted ESCC growth in vivo. (A) Tumor volumes of mouse models injected with TE-1 cells carrying sh-circ-OGDH or sh-NC. *P < 0.05, **P < 0.01, and ***P < 0.001 vs sh-NC. (B) Tumor pictures of mice injected with TE-1 cells carrying sh-circ-OGDH or sh-NC. (C) Tumor weight of mice injected with TE-1 cells carrying sh-circ-OGDH or sh-NC. **P < 0.01 vs sh-NC. (D) QRT-PCR revealed the expression of circ-OGDH, miR-615-5p, and PDX1 mRNA in xenograft tumor tissues in sh-circ-OGDH and sh-NC groups. *P < 0.05 and **P < 0.01 vs sh-NC. (E) Western blotting presented the protein level of PDX1 in xenograft tumor tissues in sh-circ-OGDH and sh-NC groups. *P < 0.05 vs sh-N.