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. 2021 Jan 22;124(8):1373–1378. doi: 10.1038/s41416-020-01228-2

Table 2.

BMD changes at the lumbar spine and total hip with associated 95% confidence intervals between baseline and 7 years according to strata and treatment allocation.

Stratum I Stratum II Stratum III
P (N = 206) A (N = 205) P value P/P (N = 64) P/R (N = 48) P value A/P (N = 53) A/R (N = 60) P value P (N = 43) A (N = 37) P value
Lumbar spine −1.37 (−2.16 to −0.57) −3.94 (−4.71 to −3.17) 0.0007 0.32 (−0.97 to 1.60) 2.83 (0.92 to 4.74) 0.175 −2.37 (−3.97 to −0.77) 1.34 (−0.11 to .78) 0.0007 3.80 (1.70 to 5.90) 2.82 (0.91 to 4.74) 0.99
Total hip −4.31 (−4.91 to −3.71) −5.06 (−5.72 to −4.40) 20.7 −3.85 (−4.87 to −2.83) −0.31 (−1.74 to 1.12) 0.0007 −3.66 (−5.02 to −2.31) −2.44 (−3.76 to −1.12) 0.99 −0.17 (−1.61 to 1.27) −0.86 (−2.74 to 1.03) 0.99

Women in stratum I had healthy BMD at baseline, those in stratum II were osteopenic, and those in stratum III were osteoporotic. P values are for a comparison between allocated treatment groups. P values are corrected for multiple comparisons.

A Anastrozole, P Placebo, R Risedronate.