Table 3.
Comparison of the Respiratory Index and Respiratory Mechanics Parameters Between the Two Groups of Patients (n=70)
| T1 | T2 | T3 | T4 | ||
|---|---|---|---|---|---|
| PaO2 | Group C | 398.01±70.78 | 171.64±81.70 | 183.36±78.46 | 402.2±77.72 |
| (mmHg) | Group L | 416.61±77.85 | 192.60±89.87 | 205.49±86.30 | 446.24±85.50 |
| P | 0.299 | 0.311 | 0.266 | 0.027 | |
| PaCO2 | Group C | 39.09±8.23 | 39.01±2.80 | 38.31±1.69 | 38.92±2.24 |
| (mmHg) | Group L | 39.95±3.01 | 39.87±2.93 | 39.13±1.78 | 39.77±2.35 |
| P | 0.229 | 0.216 | 0.053 | 0.128 | |
| A-aDO2 | Group C | 265.14±71.61 | 491.61±81.36 | 480.77±77.81 | 261.14±78.18 |
| (mmHg) | Group L | 220.45±78.71 | 469.56±89.52 | 457.60±885.62 | 216.06±85.97 |
| P | 0.278 | 0.285 | 0.240 | 0.025 | |
| OI | Group C | 398.01±70.78 | 171.64±81.70 | 183.36±78.46 | 402.2±77.72 |
| (mmHg) | Group L | 441.61±77.85 | 192.60±89.87 | 205.49±86.30 | 446.24±85.50 |
| P | 0.299 | 0.311 | 0.266 | 0.027 | |
| Ppeak | Group C | 15(14.04–15.68) | 23(21.99–24.12) | 23(22.95–24.77) | 18(16.69–17.46) |
| (cmH2O) | Group L | 17(16.19–17.87) | 23(22.67–24.70) | 22(20.95–24.96) | 15(14.23–17.12) |
| P | 0.067 | 0.389 | 0.208 | <0.001 | |
| Pplat | Group C | 15.00(12.96–14.64) | 22(20.89–22.94) | 22(20.60–22.72) | 17(12.75–13.94) |
| (cmH2O) | Group L | 16(15.15–16.96) | 21(20.90–23.70) | 23(21.70–23.56) | 16(14.73–16.47) |
| P | 0.075 | 0.191 | 0.166 | <0.001 | |
| Cst | Group C | 45.6±15.52 | 24.34±5.75 | 24.89±3.81 | 48.71±16.58 |
| (mL/cmH2O) | Group L | 37.51±12.04 | 22.37±4.64 | 22.66±4.6 | 39.03±13.76 |
| P | 0.058 | 0.119 | 0.093 | 0.057 | |
| Cdyn | Group C | 40.11±12.22 | 22.89±5.38 | 22.74±5.25 | 42.29±11.54 |
| (mL/cmH2O) | Group L | 36.06±9.54 | 21.40±4.41 | 21.09±4.05 | 37.09±9.52 |
| P | 0.054 | 0.211 | 0.144 | 0.066 |
Notes: The data are presented as means ± SD or median (interquartile range). Group C= the control group, Group L= the lidocaine group.
Abbreviations: PaO2, partial pressure of oxygen in arterial blood; PaCO2, partial pressure of carbon dioxide in arterial blood; A-aDO2, alveolar-arterial oxygen gradient; OI, oxygenation index; Ppeak, peak airway pressure; Pplat, plateau airway pressure; Cst, static lung compliance; Cdyn, dynamic lung compliance.