Table 1.
Differentially methylated regions with nominally differential gene expression
| Chr | From | To | Gene | Number of CpGs | Methylation Difference | RNAseq Fold Change | RNAseq p-value |
|---|---|---|---|---|---|---|---|
| 5 | 2748781 | 2748955 | IRX2 | 21 | −3.06% | 1.20 | 8.17E-02 |
| 9 | 126776177 | 126776282 | LHX2 | 12 | −8.22% | 1.22 | 1.46E-02 |
| 5 | 3599609 | 3599704 | IRX1 | 9 | 11.05% | 1.39 | 1.21E-03 |
| 4 | 53474 | 53566 | ZNF595 | 9 | 7.67% | 0.79 | 1.08E-02 |
| 17 | 1960987 | 1961029 | HIC1 | 8 | −11.51% | 1.25 | 7.09E-03 |
| 2 | 26785211 | 26785290 | C2orf70 | 7 | 7.44% | 1.29 | 1.31E-02 |
| 1 | 17215449 | 17215492 | CROCC | 7 | −5.45% | 1.24 | 1.85E-03 |
| 11 | 132812684 | 132812729 | OPCML | 7 | 15.93% | 0.86 | 7.03E-02 |
| 2 | 63274825 | 63274901 | OTX1 | 6 | 9.92% | 1.25 | 2.53E-02 |
| 18 | 77918229 | 77918253 | PARD6G | 6 | −10.83% | 1.51 | 3.98E-05 |
| 5 | 131607235 | 131607278 | PDLIM4 | 6 | 8.28% | 1.36 | 2.78E-03 |
| 7 | 150002 | 150037 | AC093627.10 | 5 | 8.95% | 0.84 | 2.14E-02 |
| 12 | 120654707 | 120654747 | PXN | 5 | 10.21% | 1.17 | 5.55E-02 |
| 19 | 18980163 | 18980188 | UPF1 | 5 | 10.03% | 1.07 | 2.35E-02 |
| 2 | 63275003 | 63275040 | OTX1 | 4 | 7.49% | 1.25 | 2.53E-02 |
| 17 | 76172805 | 76172850 | TK1 | 4 | 7.10% | 0.87 | 8.77E-02 |
| 8 | 37556087 | 37556121 | ZNF703 | 4 | 12.14% | 1.20 | 1.41E-02 |
| 6 | 32165134 | 32165176 | NOTCH4 | 3 | 8.58% | 1.14 | 9.81E-02 |
| 3 | 8799985 | 8800008 | OXTR | 3 | 12.55% | 1.29 | 1.35E-02 |
| 19 | 47220817 | 47220856 | PRKD2 | 3 | 5.76% | 1.33 | 3.70E-04 |
| 5 | 176877611 | 176877636 | PRR7 | 3 | 11.64% | 1.53 | 4.52E-11 |
| 4 | 6273547 | 6273577 | WFS1 | 3 | 21.42% | 1.12 | 7.12E-02 |
| 9 | 136654410 | 136654426 | VAV2 | 2 | 12.46% | 1.17 | 3.08E-02 |