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. 2021 Mar 29;15:630898. doi: 10.3389/fnhum.2021.630898

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Copyright © 2021 Haykal, Jansonius and Cornelissen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Significant difference in the rate of FD loss exhibited by visual pathways of POAG patients compared to controls. The left OR of POAG patients showed a significantly higher rate of FD loss compared to the controls. Streamlines corresponding to fixels exhibiting a significant (FWE-corrected P < 0.05) difference between groups are overlaid on representative axial (left) and sagittal (right) slices of the inter-subject population template and colored according to their p-values. Images are shown in radiologic convention. FD, fiber density.