Table 2.
The Regulatory Mechanism of circRNA
| Regulatory Mechanism | circRNA | Refs |
|---|---|---|
| circRNAs sponge miRNAs as ceRNAs | circMAT2B, circMYC, circ-CFH, circZFR, circPLEKHM3, circSLC25A16, circ CUX1, circ-FOXM1, circ_0067934, circCDR1as, etc. | [45,48,54–56,64,70,78,92,104,105] |
| circRNAs regulate gene transcription | circRNA-ENO1, circZKSCAN1 | [37,106] |
| circRNAs combine with RBPs | circDCUN1D4 | [107] |
| circRNAs encode proteins | circFNDC3B | [108] |
| circRNAs substitute their linear counterparts | circ-FBXW7 | [73] |
| circRNAs induce the nuclear translocation | circ-Amotl1 | [30] |