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. 2021 Apr 8;9(4):e001705. doi: 10.1136/jitc-2020-001705

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

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Kaplan-Meier curve for overall survival according to genotypes or centromeric and telomeric KIR content. Heterozygous individuals (AB) were compared with homozygotes (AA or BB) separately (A) or in combination (AA and BB) (B). The median overall survival among homozygotes (AA+BB) was 5.28 months and among heterozygous patients 7.60 months (p=0.015, log-rank test). Genotypes (AA and Bx) were assessed based on the centromeric and telomeric regions (C). The median overall survival among homozygotes (cAcA-tAtA or cBx-tBx) was 5.28 months, whereas among heterozygotes (cAcA-tBx or cBx-tAtA) was 8.17 months (p=0.006, log-rank test). cenA (cA) and telA (tA), centromeric and telomeric motifs of the A haplotype; cenB (cB), centromeric motif B haplotype; KIR, killer cell immunoglobulin-like receptor; telB (tB), telomeric motif of the B haplotype.