Table 7.

Univariate and multivariate analyses for overall survival

	Univariate		Multivariate
	HR (95% CI)	P value	HR (95% CI)	P value*
Genotype
AB	1
AA	2.08 (1.04 to 4.15)	0.04	2.02 (0.97 to 4.2)	0.06
BB	1.89 (1 to 3.55)	0.05	1.58 (0.79 to 3.11)	0.19
Genotype
AB	1
AA or BB	1.96 (1.13 to 3.41)	0.017	1.74 (0.97 to 3.15)	0.06
Centromere–telomere genotype
cA/tB or cB/tA	1		1
cA/tA or cB/tB	2.20 (1.23 to 3.93)	0.007	1.93 (1.02 to 3.65)	0.044
Centromere genotype
Bx/cenA	1
AA	2.31 (0.99 to 5.37)	0.05	1.67 (0.61 to 4.56)	0.31

*Multivariate analysis includes age, gender and number of metastases as covariates for overall survival; p≤0.05 denotes statistical differences.

Bx, X can be A or B haplotype; cA, centromeric motif A haplotype; cB, centromeric motif B haplotype; p-values in bold, indicates those that are lower than 0.05; tA, telomeric motif A haplotype; tB, telomeric motif of B haplotype.