Table 1.
Characteristics | Primary site | Metastatic site |
(n=8285), n (%) | (n=6743), n (%) | |
Age, years | ||
Median (range) | 69 (23–90) | 67 (19–90) |
Sex | ||
Male | 4175 (50.4) | 3424 (50.8) |
Female | 4108 (49.6) | 3316 (49.2) |
NA | 2 (0.02) | 3 (0.04) |
Histologic type | ||
Lung adenocarcinoma | 5072 (61.2) | 4578 (70.5) |
LUSC | 2099 (25.3) | 850 (12.6) |
NSCLC not otherwise specified | 849 (10.2) | 1062 (15.7) |
Lung large cell neuroendocrine carcinoma | 92 (1.1) | 131 (1.9) |
Lung adenosquamous carcinoma | 90 (1.0) | 32 (0.5) |
Pulmonary sarcomatoid carcinoma | 53 (0.6) | 53 (0.7) |
Lung large cell carcinoma | 21 (0.2) | 31 (0.5) |
Pulmonary carcinosarcoma | 9 (0.1) | 6 (0.1) |
Non-squamous NSCLC | 5942 (71.7) | 5671 (84.1) |
TPS, % | ||
0 | 3513 (42.4) | 2683 (39.8) |
1–49 | 2416 (29.2) | 1784 (26.5) |
≥50 | 2356 (28.4) | 2276 (33.8) |
Metastatic site | ||
Lymph node | NA | 2167 (32.1) |
Liver | NA | 765 (11.3) |
Brain | NA | 747 (11.1) |
Pleural fluid | NA | 520 (7.7) |
Soft tissue | NA | 493 (7.3) |
Bone | NA | 462 (6.9) |
Pleura | NA | 373 (5.5) |
Adrenal gland | NA | 231 (3.4) |
Other | NA | 985 (14.6) |
Values in italics represent the sum of Lung adenocarcinoma, NSCLC not otherwise specified and Lung large cell carcinoma, rather than represent a different histologic subtype.
LUSC, lung squamous cell carcinoma; NA, not applicable; NSCLC, non-small cell lung cancer; TPS, tumor proportion score.