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. 2021 Apr 8;9(4):e002230. doi: 10.1136/jitc-2020-002230

Table 1.

Clinicopathologic characteristics

Characteristics Primary site Metastatic site
(n=8285), n (%) (n=6743), n (%)
Age, years
 Median (range) 69 (23–90) 67 (19–90)
Sex
 Male 4175 (50.4) 3424 (50.8)
 Female 4108 (49.6) 3316 (49.2)
 NA 2 (0.02) 3 (0.04)
Histologic type
 Lung adenocarcinoma 5072 (61.2) 4578 (70.5)
 LUSC 2099 (25.3) 850 (12.6)
 NSCLC not otherwise specified 849 (10.2) 1062 (15.7)
 Lung large cell neuroendocrine carcinoma 92 (1.1) 131 (1.9)
 Lung adenosquamous carcinoma 90 (1.0) 32 (0.5)
 Pulmonary sarcomatoid carcinoma 53 (0.6) 53 (0.7)
 Lung large cell carcinoma 21 (0.2) 31 (0.5)
 Pulmonary carcinosarcoma 9 (0.1) 6 (0.1)
 Non-squamous NSCLC 5942 (71.7) 5671 (84.1)
TPS, %
 0 3513 (42.4) 2683 (39.8)
 1–49 2416 (29.2) 1784 (26.5)
 ≥50 2356 (28.4) 2276 (33.8)
Metastatic site
 Lymph node NA 2167 (32.1)
 Liver NA 765 (11.3)
 Brain NA 747 (11.1)
 Pleural fluid NA 520 (7.7)
 Soft tissue NA 493 (7.3)
 Bone NA 462 (6.9)
 Pleura NA 373 (5.5)
 Adrenal gland NA 231 (3.4)
 Other NA 985 (14.6)

Values in italics represent the sum of Lung adenocarcinoma, NSCLC not otherwise specified and Lung large cell carcinoma, rather than represent a different histologic subtype.

LUSC, lung squamous cell carcinoma; NA, not applicable; NSCLC, non-small cell lung cancer; TPS, tumor proportion score.