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In vivo anti-tumor efficacy of Cino-loaded PDA nanomedicine. (A) Tumor volume growth curves (B) optothermal response (C) tumor photo, and (D) tumor weight of LLC tumor-bearing mice after systemic administration of saline, blank NPs, free Cino (1 mg/kg), Cino-loaded PDA nanomedicine (1 mg/kg of Cino), and Cino-loaded PDA nanomedicine (1 mg/kg of Cino) treated with 808 NIR laser (2 W cm−2, 5 min). Data are presented as the mean ± SD (standard deviation, n = 6), *p < 0.05, **p < 0.01.
